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Dorzolamide hydrochloride, a nonbacteriostatic sulfonamide derivative, is the first topical carbonic anhydrase inhibitor clinically available. Dorzolamide hydrochloride. Dorzolamide is a medicine available in a number of countries worldwide. Dorzolamide is a powerful inhibitor of carbonic; aims;to compare the effects on intraocular pressure (iop) and side effects of monotherapy with either latanoprost or dorzolamide in patients with glaucoma or ; can j ophthalmol. Dorzolamide is a subnanomolar carbonic anhydrase ii inhibitor that was developed in the early 1990s as a topical agent for the treatment of glaucoma.
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